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TESTOSTERONE REPLACEMENT THERAPY · LARAMIE + TELEHEALTH

Men's Hormone Care

Low testosterone is more than a number. Treatment should be more than a prescription.

Testosterone deficiency is a clinical diagnosis, not a single lab value. It is established through symptoms and signs together with appropriately repeated laboratory testing, and the cause matters as much as the number.

Laramie Physicians Women & Wellness Clinic provides physician-guided testosterone replacement therapy in Laramie, Wyoming, with three treatment pathways: injections you administer yourself, injections given by our clinical staff at the clinic, and pellet therapy.

Pellet insertion and clinic-administered injections are performed in person in Laramie. Patients who cannot come to the clinic may be eligible for telehealth care using self-administered injection therapy. You do not need to choose a treatment before you begin — that decision follows evaluation.

  • Physician-guided
  • Lab-confirmed diagnosis
  • Laramie + telehealth
  • Individualized pathway
Get Started

2-MIN ASSESSMENT · MEN'S TESTOSTERONE PANEL REQUIRED

Prefer to talk first? Call (307) 745-8991

How you receive care

Testosterone pellet insertion and injections administered by clinical staff both require an in-person visit. Neither is a telehealth treatment.

Explore your treatment pathways

Explore the available pathways. Your clinician determines which treatment may be appropriate after evaluation.

Telehealth availability depends on clinician licensure, state law, clinical appropriateness and controlled-substance requirements. Availability is confirmed during your evaluation.

Available locally and, for eligible patients, by telehealth

Self-administered injections

Laramie Physicians branded testosterone RX product

The pathway most often used when treatment is managed remotely, and a common choice locally as well.

  • Administered at home
  • Telehealth eligible where permitted
  • Injectable route
  • Instruction provided

Injectable testosterone is one of the longest-established routes of replacement. Dose and interval are individualized based on symptoms, examination and laboratory results — this page states none of them.

Patients who choose this pathway are taught injection technique, storage and sharps disposal by the care team before starting.

Because ongoing supervision can be handled by visit or by video, this is the only pathway available to patients who cannot come to the clinic.

Get Started

Private evaluation · Laboratory confirmation when clinically appropriate · Prescription treatment is not guaranteed

At a glance

Route
Injection administered by the patient
Where care happens
Laramie clinic or telehealth, when eligible
Telehealth
Eligible where clinically and legally appropriate
Interval
Determined by your clinician
Controlled-substance status
Schedule III

Available to local patients and to eligible telehealth patients where permitted. Testosterone is a Schedule III controlled substance in the United States.

Diagnosis · AUA guideline

Low testosterone is not one low lab result

Low testosterone is established by symptoms and signs together with appropriately repeated laboratory testing — and by understanding the cause.

  1. 01

    Symptoms and signs

    Clinically relevant symptoms and physical signs consistent with testosterone deficiency.

  2. 02

    Repeat appropriate labs

    Testosterone is not measured once and acted on. Confirmation uses appropriately timed, repeated morning testing.

  3. 03

    Understand the cause

    Distinguishing primary from secondary hypogonadism, and identifying reversible contributors, changes the treatment decision.

= Clinical evaluation

Diagnostic reference point

The American Urological Association uses a total testosterone level of approximately 300 ng/dL as a reasonable cutoff supporting the diagnosis of low testosterone when it accompanies symptoms and signs.

What the number does not mean

That number is a diagnostic reference point, not an automatic treatment threshold. A single value below 300 ng/dL does not by itself mean testosterone therapy is indicated, and a value above it does not by itself rule out a hormonal problem.

Get Started

Private evaluation · Laboratory confirmation when clinically appropriate · Prescription treatment is not guaranteed

Symptom categories

What men actually report

Grouped by category, including the symptoms that are commonly attributed to testosterone but are not specific to it.

Sexual

  • Reduced sexual desire
  • Reduced frequency of sexual activity
  • Erectile difficulty
  • Reduced spontaneous erections

These symptoms can have many causes and do not by themselves establish testosterone deficiency.

Endocrine biology

How testosterone is actually produced

Testosterone is the output of a signaling axis. Where a treatment acts in that axis is what changes.

  1. 01

    Hypothalamus

    Releases GnRH in a pulsatile pattern.

  2. 02

    Pituitary

    Responds by releasing gonadotropins.

  3. 03

    LH and FSH

    LH signals testosterone production. FSH supports spermatogenesis.

  4. 04

    Testes

    Leydig cells and seminiferous tubules respond to that signal.

  5. 05

    Testosterone and spermatogenesis

    Circulating testosterone and sperm production are both outputs of the same axis.

Testosterone replacement

Adds testosterone downstream and can suppress upstream LH and FSH signaling.

This is a simplified model of endocrine signaling. Individual responses vary, and no outcome is guaranteed for any patient.

Evidence hierarchy

What the randomized evidence actually shows

Every module below states its evidence type and its limitation. Outcomes with inconclusive evidence are shown as inconclusive.

Coordinated randomized placebo-controlled trials

The Testosterone Trials

Design
7 coordinated trials
Population
Men 65+ with low testosterone
Duration
12 months

The Testosterone Trials enrolled older men with unequivocally low testosterone and symptoms, and randomized them to testosterone gel or placebo across coordinated trials examining sexual function, physical function, vitality, cognition, anemia, bone density and coronary plaque.

The sexual function trial showed improvement in sexual activity, sexual desire and erectile function relative to placebo. The bone trial showed increased volumetric bone mineral density and estimated bone strength. The anemia trial showed correction of anemia more often than placebo in men with unexplained anemia.

The vitality trial did not show a significant benefit on the primary vitality measure, and the cognition trial did not show benefit on memory in men with age-associated memory impairment.

What this does not establish

These trials studied men aged 65 and older with confirmed low testosterone over 12 months. They were not designed to establish long-term safety, and they do not describe what any individual patient will experience.

Snyder PJ, et al. Effects of Testosterone Treatment in Older Men. N Engl J Med. 2016;374(7):611-624.

Randomized, double-blind, placebo-controlled cardiovascular safety trial

TRAVERSE — cardiovascular safety

Participants
More than 5,200 men
Testosterone
7.0% major cardiovascular events
Placebo
7.3% major cardiovascular events

TRAVERSE was designed as a cardiovascular safety trial in middle-aged and older men with hypogonadism who had existing cardiovascular disease or high cardiovascular risk.

For the primary composite endpoint of major adverse cardiac events, the incidence was 7.0% with testosterone and 7.3% with placebo, meeting the trial's noninferiority criterion.

The trial also reported higher rates of certain other events in the testosterone group, including atrial fibrillation, acute kidney injury and pulmonary embolism.

What this does not establish

This does not prove testosterone has zero cardiovascular risk. It was a noninferiority safety trial in a specific population using a specific formulation, and FDA also requires class-wide blood-pressure warnings on testosterone products.

Lincoff AM, et al. Cardiovascular Safety of Testosterone-Replacement Therapy. N Engl J Med. 2023;389(2):107-117.

Where the evidence is strongest

  • Sexual activity

    Consistent effect in men with confirmed low testosterone

  • Sexual desire

    Consistent effect in randomized trials

  • Erectile function

    Smaller, more variable effect

  • Bone density

    Increased volumetric density and estimated strength

  • Anemia

    Correction more often than placebo in studied men

What testosterone therapy has not consistently proven

Being honest about the limits of the evidence is part of informed consent. For the following outcomes, guideline review describes the evidence as inconclusive.

  • Energy
  • Fatigue
  • Cognitive function
  • Diabetes measures
  • Lipids
  • General quality of life

Some men report changes in these areas. Group-level randomized evidence has not consistently demonstrated them, so they are not presented here as expected outcomes of treatment.

Get Started

Private evaluation · Laboratory confirmation when clinically appropriate · Prescription treatment is not guaranteed

Before you start

Thinking about children?

Tell us before you start testosterone.

Testosterone supplied from outside the body can suppress LH, FSH, intratesticular testosterone and sperm production. For some men this suppression is profound, and recovery after stopping is variable in both degree and time.

The Endocrine Society recommends against starting testosterone therapy in men who are planning fertility in the near term.

If having children is part of your plan — now or later — say so at the start of your evaluation. It can change which pathway is appropriate, and whether testosterone therapy is the right step at all. Our questionnaire flags this for the medical team before your visit.

Non-negotiable

No treatment described on this page guarantees fertility, sperm production or conception. Treatment decisions are made by the medical team after evaluation.

Laboratory evaluation

Laboratory evaluation

Testosterone is confirmed with appropriately timed, repeated testing rather than a single measurement, and which additional tests are appropriate depends on your history, examination and treatment pathway. Laboratory work happens as part of your clinical evaluation — you do not need any results to complete the questionnaire on this page.

  • Total testosterone

    Morning measurement, repeated for confirmation

  • Free testosterone

    When appropriate — for example with altered SHBG

  • LH

    Helps distinguish primary from secondary hypogonadism

  • FSH

    Relevant to spermatogenesis and to the cause of the deficiency

  • Prolactin

    When appropriate, based on the clinical picture

  • CBC and hematocrit

    Before and during testosterone therapy

  • PSA

    When appropriate, based on age and risk

  • Other individualized labs

    Determined by your clinician

This is a list of categories that may be considered — not a universal panel. Your clinician determines which tests apply to you and when they are repeated.

How it works

The LPWWC men's hormone pathway

  1. 01

    Questionnaire

    You tell us whether you can be seen in Laramie, what you are experiencing, what you are hoping for, and anything relevant in your history. It takes a few minutes and no lab results are required.

  2. 02

    Clinical review

    The medical team reviews your responses before your visit, including any fertility or safety considerations you flagged.

  3. 03

    Evaluation and laboratory testing

    Evaluation combines your history and examination with appropriately timed, repeated laboratory testing to confirm or rule out testosterone deficiency and identify the cause.

  4. 04

    Treatment decision

    If treatment is appropriate, your clinician discusses which pathway fits your situation, where care can be delivered, and what monitoring will look like.

  5. 05

    Treatment and monitoring

    Ongoing follow-up covers symptoms, blood pressure, hematocrit and other individualized monitoring, with adjustment over time.

In-person pathway:Laramie Physicians Women & Wellness Clinic, Laramie, WyomingTelehealth where permitted

Read before starting

Important safety information

This section is intentionally not hidden. Testosterone therapy is prescription treatment with real risks that belong in the decision.

Hematocrit and polycythemia

  • Testosterone stimulates red blood cell production and can raise hematocrit.
  • Elevated hematocrit is one of the most common reasons testosterone therapy is dose-adjusted, paused or stopped.
  • Blood counts are checked before starting and monitored during therapy as determined by your clinician.

Blood pressure

  • FDA requires class-wide labeling warnings about blood-pressure increases with testosterone products.
  • Increases in blood pressure can raise cardiovascular risk over time.
  • Blood pressure is assessed before starting and monitored during therapy.

Fertility

  • Testosterone supplied from outside the body can suppress LH, FSH, intratesticular testosterone and sperm production.
  • Suppression can be substantial, and recovery after stopping varies between men in both degree and timing.
  • Fertility plans should be discussed before treatment begins, not after.

Prostate and urinary

  • Testosterone therapy is not started in men with untreated prostate cancer without specialist involvement, and prostate assessment is individualized by age and risk.
  • Urinary symptoms should be reported to your clinician rather than assumed to be unrelated.

Sleep apnea

  • Testosterone therapy may worsen obstructive sleep apnea in some men.
  • Snoring, witnessed pauses in breathing or daytime sleepiness should be reported so they can be evaluated.

Controlled-substance status

  • Testosterone is a Schedule III controlled substance in the United States.
  • Prescribing, refills and monitoring follow federal and Wyoming requirements, which can affect how and where care is delivered.

Telehealth availability depends on clinician licensure, state law, clinical appropriateness and controlled-substance requirements. Availability is confirmed during your evaluation.

Get Started

Private evaluation · Laboratory confirmation when clinically appropriate · Prescription treatment is not guaranteed

Availability

All three pathways at a glance

  • Self-administered injections

    Available locally and, for eligible patients, by telehealth

  • Injections given at the clinic

    In-person only · Laramie, Wyoming

  • Testosterone pellet therapy

    In-person only · Laramie, Wyoming

Questions men actually ask

Men's hormone care FAQ

What is testosterone replacement therapy?

Testosterone replacement therapy is prescription treatment that supplies testosterone from outside the body to men diagnosed with testosterone deficiency.

At Laramie Physicians Women & Wellness Clinic it is offered as injections you administer yourself, injections administered by our clinical staff at the clinic, or pellet therapy.

It treats a diagnosed deficiency. It is not intended for men with normal testosterone who want higher levels.

Can I be treated by telehealth?

Eligible patients who cannot come to the clinic may be able to receive care by telehealth using self-administered injection therapy.

Pellet therapy and injections administered by clinical staff both require an in-person visit and are never provided remotely. Telehealth availability also depends on clinician licensure, state law, clinical appropriateness and controlled-substance requirements, and is confirmed during your evaluation.

What treatment options are available if I live near Laramie?

Patients who can reasonably travel to our Laramie clinic may have access to three testosterone treatment pathways, when clinically appropriate: self-administered injections, injections administered by our clinical team at the clinic, and testosterone pellet therapy.

Your medical team determines which options are appropriate after evaluation.

Do I have to give myself testosterone injections?

Not if you are able to receive care locally in Laramie. Local patients may also have the option of clinic-administered injections or pellet therapy.

For patients receiving care entirely by telehealth, self-administered injections are the available testosterone delivery pathway in this program.

Can I come to the Laramie clinic for my testosterone injections?

Yes. Local patients may choose to have testosterone injections administered by our clinical team at the clinic rather than giving injections themselves, when that treatment pathway is appropriate.

What if I am not comfortable giving myself injections?

Tell us in the Get Started questionnaire. If you live near Laramie, the care team can discuss clinic-administered injections or pellet therapy with you.

If you are receiving care remotely, your response will be available to the medical team so they can discuss the appropriate next step.

Can I receive testosterone pellet therapy by telehealth?

No. Testosterone pellet insertion is an in-person procedure performed at the Laramie clinic. Pellet therapy is available only to patients who can travel to Laramie for the procedure and are appropriate candidates.

How close do I need to live to Laramie for local treatment?

There is not a single mileage cutoff presented on the website. The important question is whether you can reasonably travel to the Laramie clinic for the in-person care your treatment pathway requires.

The Get Started questionnaire asks this near the beginning so we can show you the appropriate options.

What if I live elsewhere in Wyoming?

If you do not live within reasonable driving distance of Laramie, the questionnaire routes you to the telehealth pathway.

Availability still depends on clinical appropriateness and whether telehealth treatment can legally be provided where you live.

What if I live outside Wyoming?

You can still complete the Get Started questionnaire. Patients outside Wyoming are routed to the telehealth pathway rather than Laramie-based procedures.

Actual treatment availability depends on the medical team's ability to provide care in your state.

Can I start with telehealth and later come to Laramie for pellets or clinic injections?

Potentially. Your preferred treatment pathway can be discussed with the medical team. Procedures such as pellet insertion and clinic-administered injections require in-person care in Laramie.

What happens after I complete the Get Started questionnaire?

Your answers help us understand your location, symptoms, goals, treatment history, fertility concerns, treatment preferences and other information the care team may need.

If you continue through the standard testosterone evaluation pathway, the next step is the Men's Testosterone Panel.

What is the Men's Testosterone Panel?

The Men's Testosterone Panel is the laboratory testing step used as part of the testosterone evaluation process. It is purchased through the website for $149.

Laboratory results are reviewed together with your symptoms, history and clinical evaluation. Purchasing laboratory testing does not guarantee testosterone treatment or a prescription.

Do I need to enter my contact information before starting?

No. The questionnaire is designed to begin with simple routing questions rather than a lead form.

Your name, email and mobile number are collected later as part of checkout so you do not have to enter the same information twice.

Why does the questionnaire ask where I live first?

Location determines which treatment pathways are practical. Patients who can come to Laramie may have access to self-administered injections, clinic-administered injections and pellet therapy.

Patients receiving care remotely are routed to the telehealth pathway.

Why do you ask whether fertility is important to me?

Testosterone therapy can suppress sperm production, so fertility goals are important information for the medical team before treatment decisions are made.

Selecting a fertility concern does not by itself determine your treatment. It tells the provider that the issue should be discussed during your evaluation.

Can I tell the care team that I am interested in other treatments too?

Yes. The Get Started questionnaire can also capture interest in services such as weight loss, peptides, sexual health, hair restoration, wellness, age management and skin care.

This information helps the care team understand your broader goals without making you complete another form.

Does completing the questionnaire mean I qualify for testosterone?

No. The questionnaire helps organize your information and route you to the appropriate next step.

Testosterone therapy requires medical evaluation and appropriate laboratory findings, and a prescription is never guaranteed.

What is low testosterone?

Low testosterone, or testosterone deficiency, is a clinical condition in which consistently low testosterone occurs together with symptoms and signs consistent with deficiency.

Both parts matter. Laboratory values alone, without symptoms, do not establish the condition, and symptoms alone, without confirmed low levels, do not either.

How is low testosterone diagnosed?

Diagnosis combines symptoms and signs with appropriately timed, repeated laboratory measurement of total testosterone, plus additional testing to identify the cause.

Morning testing is used because testosterone follows a daily rhythm, and repeat testing is used because a single value can be misleading.

What does 300 ng/dL mean?

The American Urological Association uses a total testosterone level of approximately 300 ng/dL as a reasonable cutoff supporting the diagnosis of low testosterone when symptoms and signs are present.

It is a diagnostic reference point, not an automatic treatment threshold. A number alone does not determine whether treatment is appropriate.

Do I need lab results before I fill out the questionnaire?

No. The questionnaire is a routing and intake tool, not a diagnosis. Laboratory evaluation happens as part of your clinical evaluation.

If you already have recent results, bring them to your visit — but they are not required to get started.

Does testosterone therapy improve sexual function?

In men with confirmed low testosterone, randomized evidence shows improvement in sexual desire and sexual activity, with a smaller and more variable effect on erectile function.

Sexual symptoms often have contributors beyond hormones, including vascular health, medication, sleep and mood, so testosterone addresses only part of the picture.

Will testosterone therapy give me more energy?

Energy and fatigue are among the outcomes where guideline review describes the evidence as inconclusive.

The vitality trial within the Testosterone Trials did not show a significant benefit on its primary vitality measure. Some men report feeling different, but this is not presented as an expected outcome of treatment.

Is testosterone therapy safe for the heart?

TRAVERSE, a randomized cardiovascular safety trial in more than 5,200 men with hypogonadism and cardiovascular disease or high risk, found major adverse cardiac events in 7.0% of the testosterone group and 7.3% of the placebo group, meeting its noninferiority criterion.

This does not prove testosterone has zero cardiovascular risk. The trial reported higher rates of atrial fibrillation, acute kidney injury and pulmonary embolism in the testosterone group, and FDA requires class-wide blood-pressure warnings on testosterone products.

What is the risk to my blood count?

Testosterone can raise hematocrit, and elevated hematocrit is one of the most common reasons therapy is dose-adjusted, paused or stopped.

A complete blood count is checked before starting and monitored during therapy.

Will testosterone therapy affect my fertility?

Testosterone supplied from outside the body can suppress LH, FSH, intratesticular testosterone and sperm production, and in some men suppression is profound.

The Endocrine Society recommends against starting testosterone therapy in men planning fertility in the near term. Recovery after stopping varies between men in both degree and time. Tell us before you start, and the medical team will factor it into the plan.

How does pellet therapy work?

Pellets are placed under the skin during a short in-office procedure and release testosterone over an extended interval rather than daily or weekly.

Pellet insertion requires an in-person visit to the Laramie clinic and is not a telehealth treatment. Because a pellet continues releasing testosterone after insertion and cannot be readily removed, the decision is made with your clinician after evaluation.

Begin with your health — not a prescription.

Share your symptoms, history and goals. A licensed clinician determines whether hormone treatment is appropriate and which pathway fits your situation. Prescription treatment requires medical review, and treatment is not guaranteed.

Get Started

Private evaluation · Laboratory confirmation when clinically appropriate · Prescription treatment is not guaranteed

Medical notice: this page is educational and does not replace individual medical advice. Testosterone is a Schedule III controlled substance. Availability of virtual care depends on licensure, state law, controlled-substance requirements and clinical appropriateness.